Weight Change Following Diagnosis With Psychosis: A 25 Year Perspective in Greater Manchester, UK
نویسندگان
چکیده
Aims Weight gain in the months/years after diagnosis/treatment severe enduring mental illness (SMI) is a major predictor of future diabetes, dysmetabolic profile and increased cardiometabolic risk people treated with antipsychotic agents. There limited data on longer term weight change history SMI how this may differ between individuals. We here report 25-year perspective post-SMI diagnosis Greater Manchester UK, an ethnically culturally diverse community, particular focus psychosis vs bipolar affective disorder. Methods undertook anonymised search Care Record (GMCR). reviewed health records anyone who had been diagnosed for first time episode psychosis, schizophrenia, schizoaffective disorder, delusional disorder (non-affective = NAP) also BPD). analysed body mass index (BMI) period before prescription anti-psychotic medication. Results identified 9125 diagnoses above. NAP (n 5618; 37.5% female) mean age 49.3 years; BPD 4131; 63.3% 48.1 years. Follow-up was up to 25 27.0% were non-white ethnicity 17.8% BAP A higher proportion highest quintile social disadvantage 52.4% 39.5% BPD. no significant differences baseline BMI but HbA1c those 2103 where available at 40.4mmol/mol 36.7mmol/mol At 5-year follow-up 53.6% normal healthy transitioned obese / overweight 55.6% 43.7% remained 42.7 % FU NAP, 83.1% ≥30kg/m2 stayed category 81.5% there similarity overall (42.4%) (44.1%). Conclusion The results real world longitudinal cohort study suggest that changes treatment non-affective are not significantly different, highlighting importance regular physical monitoring all SMI. Using population way has potential open new avenues research psychiatry terms outcomes.
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ژورنال
عنوان ژورنال: British Journal of Psychiatry Open
سال: 2023
ISSN: ['2056-4724']
DOI: https://doi.org/10.1192/bjo.2023.192